{"symbol":"PRMT9","synonyms":["PRMT10"],"name":"protein arginine methyltransferase 9","description":"This gene encodes a type II methyltransferase. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to the guanidino nitrogen atoms of arginine. The protein encoded by this gene methylates spliceosome associated protein 145 to regulate alternative splicing and acts as a modulator of small nuclear ribonucleoprotein maturation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2017]","ncbiEntrezGeneId":90826,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/90826","proteins":[{"symbol":"ANM9_HUMAN","href":"/api/1.0/protein/ANM9_HUMAN"}],"hgncRootFamilies":[{"name":"Protein arginine methyltransferases (PRMT)","href":"/api/1.0/gene_family/Protein+arginine+methyltransferases+%28PRMT%29"}]}