{"symbol":"PRPF18","synonyms":["PRP18","HPRP18"],"name":"pre-mRNA processing factor 18","description":"Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":8559,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8559","proteins":[{"symbol":"PRP18_HUMAN","href":"/api/1.0/protein/PRP18_HUMAN"}],"hgncRootFamilies":[]}