{"symbol":"PRPF4","synonyms":["RP70","HPRP4","HPRP4P","SNRNP60","PRP4P"],"name":"pre-mRNA processing factor 4","description":"The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]","ncbiEntrezGeneId":9128,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9128","proteins":[{"symbol":"PRP4_HUMAN","href":"/api/1.0/protein/PRP4_HUMAN"}],"hgncRootFamilies":[{"name":"WD repeat domain containing (WDR)","href":"/api/1.0/gene_family/WD+repeat+domain+containing+%28WDR%29"}]}