{"symbol":"PTGDR","synonyms":["PTGDR1","AS1","ASRT1","DP1"],"name":"prostaglandin D2 receptor (DP)","description":"This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein is reported to be a receptor for prostaglandin D2, which is a mediator of allergic inflammation and allergic airway inflammation in asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]","ncbiEntrezGeneId":5729,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5729","proteins":[{"symbol":"PD2R_HUMAN","href":"/api/1.0/protein/PD2R_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}