{"symbol":"PTGDR2","synonyms":["DL1R","GPR44","CD294","CRTH2"],"name":"prostaglandin D2 receptor 2","description":"This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3\u0027 UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011]","ncbiEntrezGeneId":11251,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/11251","proteins":[{"symbol":"PD2R2_HUMAN","href":"/api/1.0/protein/PD2R2_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"},{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"}]}