{"symbol":"PTGFR","synonyms":["FP"],"name":"prostaglandin F receptor (FP)","description":"The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":5737,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5737","proteins":[{"symbol":"PF2R_HUMAN","href":"/api/1.0/protein/PF2R_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}