{"symbol":"PTPA","synonyms":[],"name":"protein phosphatase 2 phosphatase activator","description":"Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B\u0027/PR61, and B\u0027\u0027/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B\u0027 family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":5524,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gove/gene/5524","proteins":[],"hgncRootFamilies":[]}