{"symbol":"PTPN14","synonyms":["CATLPH","PTP36","PEZ"],"name":"protein tyrosine phosphatase, non-receptor type 14","description":"The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia. [provided by RefSeq, Sep 2010]","ncbiEntrezGeneId":5784,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5784","proteins":[{"symbol":"PTN14_HUMAN","href":"/api/1.0/protein/PTN14_HUMAN"}],"hgncRootFamilies":[{"name":"Phosphatases","href":"/api/1.0/gene_family/Phosphatases"}]}