{"symbol":"PTPN4","synonyms":["MEG","PTPMEG1","PTPMEG"],"name":"protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)","description":"The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":5775,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5775","proteins":[{"symbol":"PTN4_HUMAN","href":"/api/1.0/protein/PTN4_HUMAN"}],"hgncRootFamilies":[{"name":"Phosphatases","href":"/api/1.0/gene_family/Phosphatases"}]}