{"symbol":"RAB21","synonyms":[],"name":"RAB21, member RAS oncogene family","description":"This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues. [provided by RefSeq, Nov 2015]","ncbiEntrezGeneId":23011,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23011","proteins":[{"symbol":"RAB21_HUMAN","href":"/api/1.0/protein/RAB21_HUMAN"}],"hgncRootFamilies":[{"name":"Ras small GTPases superfamily","href":"/api/1.0/gene_family/Ras+small+GTPases+superfamily"}]}