{"symbol":"RABGEF1","synonyms":["RABEX-5","RABEX5"],"name":"RAB guanine nucleotide exchange factor (GEF) 1","description":"RABGEF1 forms a complex with rabaptin-5 (RABPT5; MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A; MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).[supplied by OMIM, Mar 2010]","ncbiEntrezGeneId":27342,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/27342","proteins":[{"symbol":"RABX5_HUMAN","href":"/api/1.0/protein/RABX5_HUMAN"}],"hgncRootFamilies":[{"name":"VPS9 domain containing","href":"/api/1.0/gene_family/VPS9+domain+containing"}]}