{"symbol":"RAD1","synonyms":["REC1","HRAD1"],"name":"RAD1 checkpoint DNA exonuclease","description":"This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jan 2009]","ncbiEntrezGeneId":5810,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5810","proteins":[{"symbol":"RAD1_HUMAN","href":"/api/1.0/protein/RAD1_HUMAN"}],"hgncRootFamilies":[]}