{"symbol":"RAPGEF6","synonyms":["RAGEF2","RA-GEF-2","PDZGEF2","PDZ-GEF2","KIA001LB"],"name":"Rap guanine nucleotide exchange factor (GEF) 6","description":"Enables several functions, including GTP-dependent protein binding activity; guanyl-nucleotide exchange factor activity; and phosphatidic acid binding activity. Involved in microvillus assembly; positive regulation of GTPase activity; and protein localization to plasma membrane. Located in several cellular components, including apical plasma membrane; centrosome; and endocytic vesicle. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":51735,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/51735","proteins":[{"symbol":"RPGF6_HUMAN","href":"/api/1.0/protein/RPGF6_HUMAN"}],"hgncRootFamilies":[]}