{"symbol":"RBAK","synonyms":["ZNF769"],"name":"RB-associated KRAB zinc finger","description":"This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011]","ncbiEntrezGeneId":57786,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/57786","proteins":[{"symbol":"RBAK_HUMAN","href":"/api/1.0/protein/RBAK_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}