{"symbol":"RBBP5","synonyms":["RBQ3","SWD1"],"name":"retinoblastoma binding protein 5","description":"This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2010]","ncbiEntrezGeneId":5929,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5929","proteins":[{"symbol":"RBBP5_HUMAN","href":"/api/1.0/protein/RBBP5_HUMAN"}],"hgncRootFamilies":[{"name":"WD repeat domain containing (WDR)","href":"/api/1.0/gene_family/WD+repeat+domain+containing+%28WDR%29"}]}