{"symbol":"RBM5","synonyms":["LUCA15","H37","LUCA-15","G15","RMB5"],"name":"RNA binding motif protein 5","description":"This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer. [provided by RefSeq, Oct 2011]","ncbiEntrezGeneId":10181,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10181","proteins":[{"symbol":"RBM5_HUMAN","href":"/api/1.0/protein/RBM5_HUMAN"}],"hgncRootFamilies":[{"name":"G patch domain containing (GPATCH)","href":"/api/1.0/gene_family/G+patch+domain+containing+%28GPATCH%29"},{"name":"RNA binding motif containing (RBM)","href":"/api/1.0/gene_family/RNA+binding+motif+containing+%28RBM%29"},{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}