{"symbol":"RCAN2","synonyms":["CSP2","MCIP2","ZAKI4","DSCR1L1","ZAKI-4","RCN2"],"name":"regulator of calcineurin 2","description":"This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]","ncbiEntrezGeneId":10231,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10231","proteins":[{"symbol":"RCAN2_HUMAN","href":"/api/1.0/protein/RCAN2_HUMAN"}],"hgncRootFamilies":[]}