{"symbol":"RCN1","synonyms":["RCN","HEL-S-84","PIG20","RCAL"],"name":"reticulocalbin 1, EF-hand calcium binding domain","description":"Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.[provided by RefSeq, Jan 2009]","ncbiEntrezGeneId":5954,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5954","proteins":[{"symbol":"RCN1_HUMAN","href":"/api/1.0/protein/RCN1_HUMAN"}],"hgncRootFamilies":[{"name":"EF-hand domain containing","href":"/api/1.0/gene_family/EF-hand+domain+containing"}]}