{"symbol":"RECK","synonyms":["ST15"],"name":"reversion-inducing-cysteine-rich protein with kazal motifs","description":"The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]","ncbiEntrezGeneId":8434,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8434","proteins":[{"symbol":"RECK_HUMAN","href":"/api/1.0/protein/RECK_HUMAN"}],"hgncRootFamilies":[]}