{"symbol":"REPS1","synonyms":["RALBP1","NBIA7"],"name":"RALBP1 associated Eps domain containing 1","description":"This gene encodes a signaling adaptor protein with two EH domains that interacts with proteins that participate in signaling, endocytosis and cytoskeletal changes. The encoded protein has been found in association with intersectin 1 and Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1 when intersectin 1 was isolated from clathrin-coated pits. The encoded protein has also been shown to interact with amphiphysin, a cytoplasmic protein at the surface of synaptic vesicles. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]","ncbiEntrezGeneId":85021,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/85021","proteins":[{"symbol":"REPS1_HUMAN","href":"/api/1.0/protein/REPS1_HUMAN"}],"hgncRootFamilies":[{"name":"EF-hand domain containing","href":"/api/1.0/gene_family/EF-hand+domain+containing"}]}