{"symbol":"RFX3","synonyms":[],"name":"regulatory factor X, 3 (influences HLA class II expression)","description":"This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]","ncbiEntrezGeneId":5991,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5991","proteins":[{"symbol":"RFX3_HUMAN","href":"/api/1.0/protein/RFX3_HUMAN"}],"hgncRootFamilies":[]}