{"symbol":"RGS11","synonyms":["RS11"],"name":"regulator of G-protein signaling 11","description":"The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2013]","ncbiEntrezGeneId":8786,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8786","proteins":[{"symbol":"RGS11_HUMAN","href":"/api/1.0/protein/RGS11_HUMAN"}],"hgncRootFamilies":[{"name":"Regulators of G-protein signaling (RGS)","href":"/api/1.0/gene_family/Regulators+of+G-protein+signaling+%28RGS%29"}]}