{"symbol":"RGS2","synonyms":["G0S8"],"name":"regulator of G-protein signaling 2","description":"Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis. [provided by RefSeq, Aug 2009]","ncbiEntrezGeneId":5997,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5997","proteins":[{"symbol":"RGS2_HUMAN","href":"/api/1.0/protein/RGS2_HUMAN"}],"hgncRootFamilies":[{"name":"Regulators of G-protein signaling (RGS)","href":"/api/1.0/gene_family/Regulators+of+G-protein+signaling+%28RGS%29"},{"name":"Endogenous ligands","href":"/api/1.0/gene_family/Endogenous+ligands"}]}