{"symbol":"RGS20","synonyms":["G(Z)GAP","GZ-GAP","RGSZ1","ZGAP1"],"name":"regulator of G-protein signaling 20","description":"The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]","ncbiEntrezGeneId":8601,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8601","proteins":[{"symbol":"RGS20_HUMAN","href":"/api/1.0/protein/RGS20_HUMAN"}],"hgncRootFamilies":[{"name":"Regulators of G-protein signaling (RGS)","href":"/api/1.0/gene_family/Regulators+of+G-protein+signaling+%28RGS%29"}]}