{"symbol":"RGS3","synonyms":["C2PA"],"name":"regulator of G-protein signaling 3","description":"This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTPase-activating protein that inhibits G-protein-mediated signal transduction. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. Long isoforms are largely cytosolic and plasma membrane-associated with a function in Wnt signaling and in the epithelial mesenchymal transition, while shorter N-terminally-truncated isoforms can be nuclear. [provided by RefSeq, Jan 2013]","ncbiEntrezGeneId":5998,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5998","proteins":[{"symbol":"RGS3_HUMAN","href":"/api/1.0/protein/RGS3_HUMAN"}],"hgncRootFamilies":[{"name":"Regulators of G-protein signaling (RGS)","href":"/api/1.0/gene_family/Regulators+of+G-protein+signaling+%28RGS%29"},{"name":"C2 domain containing","href":"/api/1.0/gene_family/C2+domain+containing"}]}