{"symbol":"RHBDF2","synonyms":["RHBDL6","IRHOM2","TOC","RHBDL5","TOCG"],"name":"rhomboid 5 homolog 2 (Drosophila)","description":"Predicted to enable protein transporter activity. Predicted to be involved in negative regulation of protein secretion and regulation of epidermal growth factor receptor signaling pathway. Predicted to act upstream of or within protein localization to plasma membrane and regulation of metalloendopeptidase activity. Located in plasma membrane. Implicated in palmoplantar keratoderma-esophageal carcinoma syndrome. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":79651,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/79651","proteins":[{"symbol":"RHDF2_HUMAN","href":"/api/1.0/protein/RHDF2_HUMAN"}],"hgncRootFamilies":[{"name":"Rhomboid family (RHB)","href":"/api/1.0/gene_family/Rhomboid+family+%28RHB%29"}]}