{"symbol":"RIMBP2","synonyms":["RIM-BP2","PPP1R133"],"name":"RIMS binding protein 2","description":"Predicted to enable voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels and voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential. Predicted to be a structural constituent of presynaptic active zone. Predicted to be involved in neuromuscular synaptic transmission; regulation of calcium-dependent activation of synaptic vesicle fusion; and regulation of presynaptic membrane potential. Predicted to be located in plasma membrane and synapse. Predicted to be active in calyx of Held; glutamatergic synapse; and presynaptic active zone cytoplasmic component. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":23504,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23504","proteins":[{"symbol":"RIMB2_HUMAN","href":"/api/1.0/protein/RIMB2_HUMAN"}],"hgncRootFamilies":[{"name":"Protein phosphatase 1 regulatory subunits (PPP1R)","href":"/api/1.0/gene_family/Protein+phosphatase+1+regulatory+subunits+%28PPP1R%29"}]}