{"symbol":"RIPK1","synonyms":["IMD57"],"name":"receptor (TNFRSF)-interacting serine-threonine kinase 1","description":"This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth. [provided by RefSeq, Aug 2017]","ncbiEntrezGeneId":8737,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8737","proteins":[{"symbol":"RIPK1_HUMAN","href":"/api/1.0/protein/RIPK1_HUMAN"}],"hgncRootFamilies":[]}