{"symbol":"RLIM","synonyms":["NY-REN-43","RNF12","MRX61","TOKAS"],"name":"ring finger protein, LIM domain interacting","description":"The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2009]","ncbiEntrezGeneId":51132,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/51132","proteins":[{"symbol":"RNF12_HUMAN","href":"/api/1.0/protein/RNF12_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}