{"symbol":"RNASEH2B","synonyms":["DLEU8"],"name":"ribonuclease H2, subunit B","description":"RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2). [provided by RefSeq, Nov 2008]","ncbiEntrezGeneId":79621,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/79621","proteins":[{"symbol":"RNH2B_HUMAN","href":"/api/1.0/protein/RNH2B_HUMAN"}],"hgncRootFamilies":[]}