{"symbol":"RNF169","synonyms":[],"name":"ring finger protein 169","description":"Enables K63-linked polyubiquitin modification-dependent protein binding activity; nucleosome binding activity; and ubiquitin-modified histone reader activity. Involved in double-strand break repair via homologous recombination and negative regulation of double-strand break repair. Located in cytosol; nuclear lumen; and site of double-strand break. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":254225,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/254225","proteins":[{"symbol":"RN169_HUMAN","href":"/api/1.0/protein/RN169_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}