{"symbol":"RNF6","synonyms":[],"name":"ring finger protein (C3H2C3 type) 6","description":"The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":6049,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6049","proteins":[{"symbol":"RNF6_HUMAN","href":"/api/1.0/protein/RNF6_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}