{"symbol":"RPRD1A","synonyms":["P15RS","HST3101"],"name":"regulation of nuclear pre-mRNA domain containing 1A","description":"This gene encodes a cell-cycle and transcription regulatory protein. The encoded protein interacts with the cell cycle inhibitor cyclin-dependent kinase 4 inhibitor B and may function as a negative regulator of G(1)/S phase progression. This protein also forms homo- and hetrodimers with the protein, regulation of nuclear pre-mRNA domain-containing protein 1B, to form a scaffold that interacts with the C-terminal domain of RNA polymerase II subunit B1 and regulates several aspects of transcription. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 16. [provided by RefSeq, Dec 2014]","ncbiEntrezGeneId":55197,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/55197","proteins":[{"symbol":"RPR1A_HUMAN","href":"/api/1.0/protein/RPR1A_HUMAN"}],"hgncRootFamilies":[]}