{"symbol":"RPS4X","synonyms":["SCR10","DXS306","CCG2","RPS4","SCAR"],"name":"ribosomal protein S4, X-linked","description":"Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":6191,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6191","proteins":[{"symbol":"RS4X_HUMAN","href":"/api/1.0/protein/RS4X_HUMAN"}],"hgncRootFamilies":[{"name":"S ribosomal proteins (RPS)","href":"/api/1.0/gene_family/S+ribosomal+proteins+%28RPS%29"}]}