{"symbol":"RS1","synonyms":["XLRS1"],"name":"retinoschisin 1","description":"This gene encodes an extracellular protein that plays a crucial role in the cellular organization of the retina. The encoded protein is assembled and secreted from photoreceptors and bipolar cells as a homo-oligomeric protein complex. Mutations in this gene are responsible for X-linked retinoschisis, a common, early-onset macular degeneration in males that results in a splitting of the inner layers of the retina and severe loss in vision. [provided by RefSeq, Oct 2008]","ncbiEntrezGeneId":6247,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6247","proteins":[{"symbol":"XLRS1_HUMAN","href":"/api/1.0/protein/XLRS1_HUMAN"}],"hgncRootFamilies":[]}