{"symbol":"RSPH10B2","synonyms":[],"name":"radial spoke head 10 homolog B2 (Chlamydomonas)","description":"This gene encodes a protein component of the radial spoke head in flagella and motile cilia. Eukaryotic flagella and motile cilia share a common 9 + 2 structure, in which nine peripheral microtubule doublets (MTDs) surround a central-pair of microtubules (CP), with radial spokes connecting the MTDs to the CP. The radial spoke is a multi-protein complex that works as a mechanochemical transducer between the CP and the MTDs. The radial spoke contributes to the regulation of the activity of dynein motors, and thus to flagellar motility. PMID: 22754630 provides a good review of radial spokes. [provided by RefSeq, Jul 2017]","ncbiEntrezGeneId":728194,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/728194","proteins":[{"symbol":"R10B2_HUMAN","href":"/api/1.0/protein/R10B2_HUMAN"}],"hgncRootFamilies":[]}