{"symbol":"RUVBL2","synonyms":["INO80J","TIP48","RVB2","TIH2","CGI-46","ECP-51","TIP49B","REPTIN","ECP51","TAP54-beta"],"name":"RuvB-like AAA ATPase 2","description":"This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":10856,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10856","proteins":[{"symbol":"RUVB2_HUMAN","href":"/api/1.0/protein/RUVB2_HUMAN"}],"hgncRootFamilies":[{"name":"ATPases","href":"/api/1.0/gene_family/ATPases"},{"name":"INO80 complex subunits (INO80)","href":"/api/1.0/gene_family/INO80+complex+subunits+%28INO80%29"}]}