{"symbol":"RYR2","synonyms":["ARVC2","VTSIP","RYR-2"],"name":"ryanodine receptor 2 (cardiac)","description":"This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":6262,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6262","proteins":[{"symbol":"RYR2_HUMAN","href":"/api/1.0/protein/RYR2_HUMAN"}],"hgncRootFamilies":[{"name":"EF-hand domain containing","href":"/api/1.0/gene_family/EF-hand+domain+containing"},{"name":"Ion channels","href":"/api/1.0/gene_family/Ion+channels"}]}