{"symbol":"S100A7","synonyms":["PSOR1","S100A7C"],"name":"S100 calcium binding protein A7","description":"The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014]","ncbiEntrezGeneId":6278,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6278","proteins":[{"symbol":"S10A7_HUMAN","href":"/api/1.0/protein/S10A7_HUMAN"}],"hgncRootFamilies":[{"name":"S100 calcium binding proteins (S100)","href":"/api/1.0/gene_family/S100+calcium+binding+proteins+%28S100%29"},{"name":"EF-hand domain containing","href":"/api/1.0/gene_family/EF-hand+domain+containing"}]}