{"symbol":"S1PR1","synonyms":["D1S3362","CD363","EDG-1","S1P1","EDG1","CHEDG1"],"name":"sphingosine-1-phosphate receptor 1","description":"The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]","ncbiEntrezGeneId":1901,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1901","proteins":[{"symbol":"S1PR1_HUMAN","href":"/api/1.0/protein/S1PR1_HUMAN"}],"hgncRootFamilies":[{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}