{"symbol":"SAMD7","synonyms":[],"name":"sterile alpha motif domain containing 7","description":"Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; chromatin binding activity; and histone binding activity. Predicted to be involved in negative regulation of DNA-templated transcription; negative regulation of gene expression, epigenetic; and retinal rod cell development. Predicted to be located in cytoplasm. Predicted to be part of PRC1 complex. Predicted to be active in nucleus. Implicated in macular degeneration. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":344658,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/344658","proteins":[{"symbol":"SAMD7_HUMAN","href":"/api/1.0/protein/SAMD7_HUMAN"}],"hgncRootFamilies":[{"name":"Sterile alpha motif (SAM) domain containing (SAMD)","href":"/api/1.0/gene_family/Sterile+alpha+motif+%28SAM%29+domain+containing+%28SAMD%29"}]}