{"symbol":"SAMHD1","synonyms":["DCIP","MOP-5","SBBI88","HDDC1","CHBL2","hSAMHD1"],"name":"SAM domain and HD domain 1","description":"This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010]","ncbiEntrezGeneId":25939,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/25939","proteins":[{"symbol":"SAMH1_HUMAN","href":"/api/1.0/protein/SAMH1_HUMAN"}],"hgncRootFamilies":[{"name":"Sterile alpha motif (SAM) domain containing (SAMD)","href":"/api/1.0/gene_family/Sterile+alpha+motif+%28SAM%29+domain+containing+%28SAMD%29"}]}