{"symbol":"SART3","synonyms":["TIP110","RP11-13G14","P110(NRB)","DSAP1"],"name":"squamous cell carcinoma antigen recognized by T cells 3","description":"The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":9733,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9733","proteins":[{"symbol":"SART3_HUMAN","href":"/api/1.0/protein/SART3_HUMAN"}],"hgncRootFamilies":[{"name":"RNA binding motif containing (RBM)","href":"/api/1.0/gene_family/RNA+binding+motif+containing+%28RBM%29"}]}