{"symbol":"SCAMP4","synonyms":["SCAMP-4"],"name":"secretory carrier membrane protein 4","description":"Secretory carrier membrane proteins (SCAMPs) are widely distributed integral membrane proteins implicated in membrane trafficking. Most SCAMPs (e.g., SCAMP1; MIM 606911) have N-terminal cytoplasmic NPF (arg-pro-phe) repeats, 4 central transmembrane regions, and a short C-terminal cytoplasmic tail. These SCAMPs likely have a role in endocytosis that is mediated by their NPF repeats. Other SCAMPs, such as SCAMP4, lack the NPF repeats and are therefore unlikely to function in endocytosis (summary by Fernandez-Chacon and Sudhof, 2000 [PubMed 11050114]).[supplied by OMIM, Feb 2011]","ncbiEntrezGeneId":113178,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/113178","proteins":[{"symbol":"SCAM4_HUMAN","href":"/api/1.0/protein/SCAM4_HUMAN"}],"hgncRootFamilies":[{"name":"Secretory carrier membrane proteins (SCAMP)","href":"/api/1.0/gene_family/Secretory+carrier+membrane+proteins+%28SCAMP%29"}]}