{"symbol":"SCO2","synonyms":["PD-ECGF","MYP6","TdRPase","CEMCOX1","Gliostatin","TYMP","SCO1L"],"name":"SCO2 cytochrome c oxidase assembly protein","description":"Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors; this gene encodes one of the COX assembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy and myopia 6. [provided by RefSeq, Oct 2014]","ncbiEntrezGeneId":9997,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9997","proteins":[{"symbol":"SCO2_HUMAN","href":"/api/1.0/protein/SCO2_HUMAN"}],"hgncRootFamilies":[{"name":"Mitochondrial respiratory chain complex assembly factors","href":"/api/1.0/gene_family/Mitochondrial+respiratory+chain+complex+assembly+factors"}]}