{"symbol":"SCRIB","synonyms":["SCRIB1","CRIB1","VARTUL","SCRB1"],"name":"scribbled planar cell polarity protein","description":"This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011]","ncbiEntrezGeneId":23513,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23513","proteins":[{"symbol":"SCRIB_HUMAN","href":"/api/1.0/protein/SCRIB_HUMAN"}],"hgncRootFamilies":[]}