{"symbol":"SDCBP2","synonyms":["SITAC18","ST-2","SITAC"],"name":"syndecan binding protein (syntenin) 2","description":"The protein encoded by this gene contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The encoded protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Read-through transcription also exists between this gene and the upstream FKBP1A (FK506 binding protein 1A, 12kDa) gene, as represented in GeneID:100528031. [provided by RefSeq, Sep 2011]","ncbiEntrezGeneId":27111,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/27111","proteins":[{"symbol":"SDCB2_HUMAN","href":"/api/1.0/protein/SDCB2_HUMAN"}],"hgncRootFamilies":[]}