{"symbol":"SELENOV","synonyms":[],"name":"selenoprotein V","description":"This gene encodes a selenoprotein containing a selenocysteine (Sec) residue, which is encoded by the UGA codon that normally signals translation termination. The 3\u0027 UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is specifically expressed in the testis. It belongs to the SelWTH family, which possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif, suggesting a redox function for this gene. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Apr 2017]","ncbiEntrezGeneId":348303,"ncbiEntrezGeneUrl":"https://ncbi.nlm.nih.gov/gene/348303","proteins":[],"hgncRootFamilies":[]}