{"symbol":"SELL","synonyms":["CD62L","LSEL","PLNHR","LEU8","LAM1","LECAM1","LNHR","LYAM1","TQ1"],"name":"selectin L","description":"This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]","ncbiEntrezGeneId":6402,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6402","proteins":[{"symbol":"LYAM1_HUMAN","href":"/api/1.0/protein/LYAM1_HUMAN"}],"hgncRootFamilies":[{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"}]}