{"symbol":"SEMA4D","synonyms":["C9ORF164","CD100","COLL4","SEMAJ","COLL-4","M-SEMA-G"],"name":"sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D","description":"Enables identical protein binding activity; semaphorin receptor binding activity; and transmembrane signaling receptor activity. Involved in several processes, including ossification involved in bone maturation; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and regulation of neuron projection development. Located in plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":10507,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10507","proteins":[{"symbol":"SEM4D_HUMAN","href":"/api/1.0/protein/SEM4D_HUMAN"}],"hgncRootFamilies":[{"name":"Semaphorins (SEMA)","href":"/api/1.0/gene_family/Semaphorins+%28SEMA%29"},{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"},{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"}]}